vitiate

/ˈvi-shē-ˌāt/

Latin vitiatus, past participle of vitiare, from vitium fault, vice

verb

  1. to make faulty or defective : impair

  2. to debase in moral or aesthetic status

  3. to make ineffective

the comic impact is vitiated by obvious haste

debase vitiate deprave corrupt debauch pervert mean to cause deterioration or lowering in quality or character. debase implies a loss of position, worth, value, or dignity. vitiate implies a destruction of purity, validity, or effectiveness by allowing entrance of a fault or defect.