defeat
/di-ˈfēt/
verb
to win victory over : beat
frustrate
nullify
defeated their archrivals in the championship game
noun
frustration by nullification or by prevention of success
an overthrow especially of an army in battle
the loss of a contest
The bill suffered defeat in the Senate.
idiom
to make (something) pointless
It would defeat the purpose of having a nice car if you never got to drive it.