affliction

/ə-ˈflik-shən/

Middle English affliccioun "misery, distress, self-inflicted pain," borrowed from Anglo-French afflicion, borrowed from Late Latin afflīctiōn-, afflīctiō, from Latin afflīgere "to afflict-tiōn-, -tiō, suffix of action nouns

noun

  1. a cause of persistent pain or distress

  2. great suffering

  3. the state of being afflicted by something that causes suffering

a mysterious affliction